Antifungal Effect of Flavonoid 5, 7, 4’- Trimethoxyflavone against Candida krusei Strains.
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Date
2015
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Abstract
Most of the flavonoids are considered as constitutive antimicrobial ingredients, especially those
belonging to prenylated flavonoids, flavones and isoflavones. In the study, the flavonoid 5,7,4’-
trimethoxyflavone was evaluated for its antifungal effects. Four fungal strains were used in the
study for activities, Candida krusei – LM 9700, Candida krusei – LM 656, Candida krusei– LM 13
and Candida krusei – LM08. All the microorganism strains were obtained from the Laboratory of
Mycology collection. Microdilution method was used for antifungal assay of the flavonoid. The
results were also compared with the standard drug, Nistatin (100 UI/mL). The obtained results
showed activity fungistatic against Candida krusei strains.
Description
Keywords
Flavonoid, nistatin, antifungal, Candida krusei
Citation
Filho Abrahão Alves de Oliveira, Fernandes Heloísa Mara Batista, Sousa Janiere Pereira de, Maia Gabriela Lemos de Azevedo , Filho José Maria Barbosa, Assis Thais Josy Castro Freire de, Pêssoa Hilzeth Luna Freire, Lima Edeltrudes Oliveira. Antifungal Effect of Flavonoid 5, 7, 4’- Trimethoxyflavone against Candida krusei Strains. International Journal of TROPICAL DISEASE & Health. 2015; 5(2): 136-140.