Does thyroid function have any relation with components of metabolic syndrome.
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Date
2015-10
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Abstract
Background: Obesity, insulin resistance, physical inactivity, advanced age and hormonal disturbances have been
suggested to be the underlying risk factors for the development of metabolic syndrome. Thyroid dysfunction can
cause obesity, and can in turn lead to metabolic syndrome and can also be a cause of lipid abnormalities. Hence we
tried to study the effect of thyroid function on the components of metabolic syndrome.
Methods: Blood pressure, waist circumferences, HDL cholesterol and triglycerides were measured in all patients.
TSH was measured and on its basis patients were divided in three groups: euthyroid, hypothyroid and subclinical
hypothyroid.
Results: There were 28 females and 22 males. Mean BMI was 31.51±5.21 kg/m2. The mean systolic blood pressure
was 139.04±26.67 mm Hg and the diastolic pressure was 88.32±14.95 mm Hg. Mean waist circumference was
102±10.1 cm & mean waist: hip ratio was 0.97±0.094. HDL <50 in males and <40 in females in Euthyroid showed
statistical significance (p value 0.05). Other components did not gain a statically significance. Comparing gender wise
Subclinical hypothyroidism patients with Euthyroid patients, females having subclinical hypothyroidism are more
likely to have metabolic syndrome (p value =0.03). This is not so in case of males.
Conclusions: Female patients having subclinical hypothyroidism have higher chances of have metabolic syndrome as
compared to males. Euthyroid patients with metabolic syndrome had low cholesterol. Other components of metabolic
syndrome had no statically significance with thyroid function.
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Keywords
Metabolic syndrome, Subclinical hypothyroidism, Euthyroid, Overt hypothyroid
Citation
Shah Yash, Vadher Abhishek, Reddy Karthik, Chapadia Harsh. Does thyroid function have any relation with components of metabolic syndrome. International Journal of Research in Medical Sciences. 2015 Oct; 3(10): 2682-2685.