Antihypertensive agents in systemic hypertension associated with Type 2 diabetes in a tertiary care hospital.
Loading...
Date
2015-05
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Background: Hypertension and diabetes mellitus are both chronic disorders and
when they occur as co-morbidities create havoc by presenting with a plethora of
morbidity and mortality. Both require drug treatment over a long period of time,
which calls for stringent analysis of prescribing trends of the same.
Objectives: The present study was intended to analyze prescribing pattern and
establish prescribing trends of anti-hypertensive drugs (AHD) in hypertensive
diabetic patients.
Methods: The present study was a record based, randomized, non-interventional
study of 2 years duration conducted at a tertiary care hospital of central India.
Prescriptions from 400 case records of hypertensive diabetics were obtained
from the medical record section. Demographic details, blood pressure, and AHDs
prescribed were systematically entered in pre-validated case record form. All data
were thoroughly analyzed for fallacies and appropriateness.
Results: Among 400 patients, 221 were males, and 179 were females. Monotherapy
was used in 366 (91.5%) patients while combination therapy was used in 34 (8.5%)
patients. Most commonly used combination was angiotensin converting enzyme
inhibitor (ACEI)+calcium channel blocker (CCB), while in monotherapy
CCB≥ACEI>beta blocker>diuretic>angiotensin II receptor blocker were most
commonly prescribed.
Conclusion: The present study represents trend and attitude of physicians in
prescribing AHDs. On comparing with Joint National Committee 7 guidelines, the
majority of the cases deviated from the guidelines, mostly in a choice of AHDs and
Fixed dose combination.
Description
Keywords
Hypertension, Antihypertensive agents, Diabetes, Joint National Committee 7
Citation
Shende Tanaji R, Siddiqui Riyaz A, Mahajan Harshal M. Antihypertensive agents in systemic hypertension associated with Type 2 diabetes in a tertiary care hospital. International Journal of Basic & Clinical Pharmacology. 2015 May-Jun; 4(3): 510-514.