Anti-inflammatory Activity of Butanolic Extract of Albizia lebbeck.
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Date
2014-12
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Abstract
Albizia lebbeck is a tree widely distributed in India and is also found in South Africa, South
America and Australia. As in Indian traditional system as folk medicine, this plant is used
to treat several inflammatory pathologies such as asthma, arthritis and burns. Study of
other species this same genus has demonstrated an anti-inflammatory activity of crude
extract, which, in some work has been attributed to the presence of saponins. In order to
confirm these findings a study of phytochemical profile was realized and a rich extract in
saponins, butanolic extract, was obtained and its anti-inflammatory activity was evaluated
through measured by inhibition of carrageenan-induced mouse paw oedema, using
dexamethasone as reference compound. The extract exhibited a moderate control of the
both phase of inflammation, provoking an inhibition of edema formation. However, the
butanolic extract exhibited lesser activity than reference compound dexamethasone. The
results obtained suggest a significant antiinflamatory property of the butanolic extract of
Albizia lebbeck, justifying the use of this plant in the traditional medicine for the treatment
of inflammatory conditions and confirm their saponins as bioactive product.
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Keywords
Albizia lebbeck, anti-inflammatory activity, saponins, butanolic extract
Citation
Barbosa Antony de Paula.Anti-inflammatory Activity of Butanolic Extract of Albizia lebbeck. European Journal of Medicinal Plants. 2014 Dec; 4(12): 1400-1407.