Syzygium sp (Myrtaceae) Extracts: Inhibition of Alpha Amylase.
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Date
2014-01
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Abstract
Aims: The aims of this study were: a) prepare crude extracts of commercial teas
Syzygium sp by different methods (maceration, decoction and infusion) in different
proportions (1:20, 1:50 and 1:100) and b) submit them the inhibition assays digestive
enzyme alpha-amylase before and after exposure to a simulated gastric fluid.
Place and Duration of Study: Laboratório de Bioquímica, Instituto de Ciências
Biológicas e Naturais, Universidade Federal do Triângulo Mineiro, Brazil, between August
2012 and July 2013.
Methodology: Five samples of Syzygium sp teas were purchased commercially from
pharmacies, drugstores and health food stores.
Results: In the first step - inhibition of enzymatic extracts of the teas without simulated
gastric fluid - the results showed significant inhibition of alpha-amylase (mean 92.84%,
CV = 3.86%). However, when these extracts were placed in contact with the simulated
gastric fluid was observed decreased inhibition of alpha – amylase, suggesting a possible reduction of hypoglycemic potential of these teas under physiological conditions.
Conclusion: Aqueous extract Syzygium sp have high percentages of inhibition of the
enzyme amylase, suggesting a potential hypoglycemic effect. Additional studies aiming at
elucidating the chemical compounds present in the extracts of Syzygium sp using
chromatographic techniques will be performed.
Description
Keywords
Syzygium, diabetes, amylase, gastric fluid
Citation
Freitas Tuanny Cavatão de, Pereira Chrystian Araújo, Pereira Luciana Lopes Silva. Syzygium sp (Myrtaceae) Extracts: Inhibition of Alpha Amylase. European Journal of Medicinal Plants. 2014 Jan; 4(1): 116-125.