Preliminary Phytochemical, Antibacterial and Antifungal Properties of Alafia barteri Stem Grown in Nigeria.
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Date
2011-04
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Abstract
The preliminary phytochemical studies of Alafia barteri stem extracts revealed the presence of
reducing sugar, steroids, glycosides, flavonoids and anthraquinones. Hexane, ethylacetate and
methanol successive extracts of A. barteri stem showed inhibition on the six test bacteria.
Escherichia coli and Pseudomonas aeruginosa were sensitive to methanol extract at
concentrations ranging from 25 to 200mg/ml using agar disk diffusion procedure, while hexane
and ethylacetate extracts of the plant inhibited the growth of Escherichia coli and Pseudomonas
aeruginosa at concentrations between 50 and 200mg/ml. Hexane and ethylacetate extracts
showed lower inhibition on Staphyloccocus aureus and Bacillus subtilis (gram positive), and
Klebsiellae pneumonae (gram negative). Meanwhile, methanol extract exhibited antibacterial
properties on Staphyloccocus aureus at concentrations between 50 and 200mg/ml, and Bacillus
subtilis, Klebsiellae pneumonae and Salmonellae typhii at concentrations between 100 and
200mg/ml. The three extracts exhibited higher antifungal properties on Candida albicans,
Aspergillus niger, Rhizopus stolon, Penicillum notatum, Tricophyton rubrum and Epidermophyton
floccosum with activity comparable to that of the reference drug tioconazole trosyd.
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Alafia barteri, bioactivity, phytochemical screening, agar diffusion method, sensitivity
Citation
Hamid A A, Aiyelaagbe O O. Preliminary Phytochemical, Antibacterial and Antifungal Properties of Alafia barteri Stem Grown in Nigeria. European Journal of Medicinal Plants. 2011 Apr-June; 1(2): 26-32.