Synthesis, characterization, antimicrobial activities and DNA–binding studies of some Ru (III) complexes of schiff bases.
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Date
2012-04
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Abstract
A new ruthenium (III) Schiff base complexes of the type [RuX2 (PPh3)2(L)] (where X =
Cl or Br; L = monobasic bidentate Ligand) have been synthesized. All the complexes were characterized
by analytical, IR, electronic and EPR spectral studies. An octahedral geometry has been tentatively
proposed to all the new complexes. Further the ligands and complexes were subjected to antimicrobial
activity studies. The new complexes have been tested to find out the DNA – binding by electronic
spectral studies and anti cancer effect.
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Keywords
Monobasic bidentate Schiff bases, ruthenium(III) complexes, spectral studies, antimicrobial activities, DNA binding and anticancer studies
Citation
Raju V V, Balasubramaniana K P, Jayabalakrishnan C, Chinnusamy V. Synthesis, characterization, antimicrobial activities and DNA–binding studies of some Ru (III) complexes of schiff bases. International Journal of Applied Biology and Pharmaceutical Technology. 2012 Apr-Jun; 3(2): 76-87.