In vitro Antibacterial Activity of Cichorium intybus against some Pathogenic Bacteria.
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Date
2013-10
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Abstract
The root and leaf extracts of Cichorium intybus were investigated for antibacterial activity
against gram negative pathogenic bacteria viz. Escherichia coli and Pseudomonas
aeruginosa. The sensitivity was analyzed using Disk diffusion method at various
concentrations where zone of inhibition was compared with the standard drug
Cephotaxime. The extracts showed a wide spectrum of inhibition against the test
pathogens. Methanolic extract of root and leaf proves to have the strongest antibacterial
activity. Antibacterial activity of the test extracts at different inhibitory concentration varied
significantly at 0.05 level of significance. The maximum activity was recorded at 200mg/ml
concentration, the activity decreased with the decrease in the concentration of the extract.
The present study reveals that the root and leaf extracts of Cichorium intybus would exert
several beneficial effects by virtue of their antibacterial activity and could potentially be
exploited as a source of natural antibacterial.
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Keywords
Antibacterial activity, cephotaxime, Cichorium intybus, disk diffusion, sensitivity
Citation
Verma Renu, Rawat Ashish, Ganie Showkat Ahmad, Agnihotri Rajneesh K, Sharma Rajendra, Mahajan Surabhi, Gupta Ankur. In vitro Antibacterial Activity of Cichorium intybus against some Pathogenic Bacteria. British Journal of Pharmaceutical Research. 2013 Oct; 3(4): 767-775.