Antimicrobial Susceptibility Pattern of Some Recently Isolated Serovars of Salmonellae in Jos, Nigeria.
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Date
2014-12
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Abstract
Aim: To determine the salmonellae serovars circulating in North Central Nigeria and their
treatability with commonly used antimicrobial agents.
Study Design: Investigative
Place and Duration of Study: Samples were collected and processed at the Jos
University Teaching Hospital (JUTH), Plateau State, Nigeria between 2006 and 2011.
Methodology: Standard microbiological tests were used for isolation, identification and
serotyping of salmonellae from 3509 blood and 5426 stool samples collected from patients
attending Jos University Teaching Hospital (JUTH), Jos between 2006 and 2011. Identified
serovars were subjected to antimicrobial susceptibility testing using disc diffusion method.
Results: 89 Salmonella isolates were obtained from 8935 samples. Blood and stool
cultures yielded 1.4% and 0.70% salmonellae respectively. The highest number of isolates was from age group 0-9 years 30(33.7%) while patients aged 70 and above
accounted for the least number of isolates 1(1.1%). Males accounted for more isolates
49(55.1%) than females 40(44.9%) (p<0.05). The 89 isolates encountered comprised 39
serovars of which 74(83.1%) were non-typhoidal. Frequently isolated serovars were
S. typhimurium and S. bargny 11(12.3%) each, S. typhi 7(7.7%) and S. paratyphi B and S.
saint Paul 6(6.7%) each. Rare serovars isolated included S. Lagos, S. aba, S. kisii, S.
okerara and S. aminatu 1(1.1) each. All isolates were susceptible to ciprofloxacin and
ceftriaxone( MIC≤ 1μg/mL) while more than 50% of the frequently isolated serovars were
resistant to chloramphenicol, amoxicillin and cotrimoxazole.
Conclusions: This study reveals a high occurrence of invasive non-typhoidal, multi-drug
resistant Salmonella serovars. However, susceptibility to ciprofloxacin and ceftriaxone is
completely preserved and can be used for empirical treatment of salmonellosis.
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Keywords
Salmonella, serovars, Jos, Nigeria, antimicrobial susceptibility
Citation
Opajobi Solomon O, Kandakai-Olukemi Yvonne T, Banwat Edmund B, Egah Daniel Z, Chollom Solomon C, Mawak John D. Antimicrobial Susceptibility Pattern of Some Recently Isolated Serovars of Salmonellae in Jos, Nigeria. British Microbiology Research Journal. 2014 Dec; 4(12): 1500-1510.