Clinical and Diagnostic Significance of Methicillin-resistant Staphylococcus aureus Infection in Bangladesh: A Systematic Review.
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Date
2014-07
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Abstract
Background: Accurate diagnosis of Methicillin-resistant Staphylococcus aureus (MRSA)
is essential for the clinician. In Bangladesh MRSA creates a great problem for the
treatment of infection.
Objective: The purpose of the present study was to observe the clinical and diagnostic
significance of MRSA infection in Bangladesh.
Design: Systematic review of published articles in Bangladesh.
Data Sources: PubMed (Medline), Embase, Scopus, Web of Science, the Cochrane
Library, and the World Health Organization (WHO) Regional Databases (African, eastern
Mediterranean, Latin American and Caribbean, western Pacific, and southeast Asian
regions) as well as Google Scholar, Banglajol, Asiajol.
Review Methods: The search was restricted to full articles published from January 2000
(publication date of the first study identified by the research) to December 2013. Studies were excluded that did not provide appropriate data on the prevalence of MRSA. Only
English language was applied.
Result: A total number of 125 studies were identified during systematic review which
were relevant to the present research question and among these only 14 studies were
met the criteria for analysis. The level of evidence and freedom from bias of these studies
were generally low. MRSA was diagnosed phenotypic in most of the articles. Majority
were isolated from skin wound. The isolation rate of MRSA among all culture isolates
ranged from 4.8-78.7%. From all studies diagnosis of MRSA infection was done from
hospital setting; however, only two studies had been reported from community settings
though the CDC definition was not followed in either study.
Conclusion: Significance of methicillin-resistant Staphylococcus aureus infection in
Bangladesh is very high leading to a huge clinical as well as laboratory burden in the
heath care facilities as well as in the community settings of Bangladesh.
Description
Keywords
Methicillin-resistant Staphylococcus aureus, CA-MRSA, HA-MRSA, clinical significance, diagnostic significance, systematic review
Citation
Yusuf M Abdullah, Sattar AFM Arshedi, Habib Zakir Husain, Roy Sushmita. Clinical and Diagnostic Significance of Methicillin-resistant Staphylococcus aureus Infection in Bangladesh: A Systematic Review. British Microbiology Research Journal. 2014 July; 4(7): 785-797.