Changes in Some Testicular Biometric Parameters and Testicular Function in Cadmium Chloride Administered Wistar Rats.
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Date
2013-10
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Abstract
Introduction: Recently there has been an increased association between environmental
factors and male infertility.
Aims: In the present study, the effect of changes in testicular biometric parameters
(weight and volume) and testicular function (Sperm count, morphology, testosterone
level) in Cadmium chloride administered Wistar rats was studied.
Methodology: Twenty male albino Wistar rats were randomized into four groups (n=5).
Group A (control) received rat chow and water, while Group B, C and D received
15mg/L, 20mg/L and 25mg/L of Cadmium chloride respectively for 6 weeks.
Result: There was a significant (P=.05) and dose dependent decrease in testicular
function parameters in the rats and a significant (P=.05) and positive correlation between
the biometric parameters and testicular function.
Conclusion: The findings showed that Cadmium chloride has a deleterious effect on
testicular function and biometric parameters of the testes may be important in the
assessment of testicular function.
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Keywords
Cadmium chloride, male infertility, testicular weight, testicular volume
Citation
Ekhoye E I, Nwangwa E K, Aloamaka C P. Changes in Some Testicular Biometric Parameters and Testicular Function in Cadmium Chloride Administered Wistar Rats. British Journal of Medicine and Medical Research. 2013 Oct-Dec; 3(4): 2031-2041.