Expressional Evaluation of Androgen Receptor in Transitional Cell Carcinoma of Urinary Bladder Patients.
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Date
2011-10
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Abstract
The study was undertaken to evaluate the possible role of Androgen Receptor (AR) in
relation to tumor grade, age, sex and urinary bladder cancer risk. Expression of AR
detected by immunohistochemistry in 125 Transitional Cell Carcinoma and 100 control
cases. Expression of AR was noticed in 28.8% cases. AR increased with increasing
tumor grade. Expression of AR was seen to be significantly higher in male in the age
group ≥ 50 years (p < 0.05). AR expression was found to be associated significantly
with the tumor grades, age and sex suggesting that AR may be used as prognostic
markers in the treatment of urinary bladder carcinomas.
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Keywords
Androgen receptor, smoking, transitional cell carcinoma, urinary bladder, IHC
Citation
Rahmani Arshad, Alzohairy Mohammad, Mandal A K, Rizvi Moshahid A. Expressional Evaluation of Androgen Receptor in Transitional Cell Carcinoma of Urinary Bladder Patients. British Journal of Medicine and Medical Research. 2011 Oct; 1(4): 233-238.