Antioxidant status and serum total protein levels in elderly women.
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Date
2011-07
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Abstract
Background and Objective: The imbalance between reactive oxygen species production and antioxidant
defense determines the degree of oxidative stress. Vitamin C and GSH are important antioxidants,
protects the cells from toxins such as free radicals. A total serum protein test measures the total amount of
protein in the blood. The objective of the present study was to analyze the oxidative stress in elderly
women, by evaluating the antioxidant status (vitamin c and glutathione), total protein and albumin levels.
Materials and Methods: The study group includes, Group 1 and Group 2 with 50 institutionalized and
50 non- institutionalized women’s belonging at the age group of 50-65 years respectively. 2ml of venous
blood was collected for the analysis of the level of Vitamin C, Total protein, Albumin and Glutathione by
standard methods. Data were analyzed for the statistical significance using one way ANOVA. p<0.05 was
considered significant. Result: The level of Vitamin C, Total proteins and Glutathione were significantly
declined (p=0.03, p=0.01 and p=0.006) in institutionalized women’s as compared to non-institutionalized
women’s. Conclusion: Antioxidant and Total proteins are considered to be important in the maintenance
of health. Antioxidant and Total protein levels were showing general tendency to decrease during ageing.
Description
Keywords
Total antioxidant, Glutathione, Total protein, Free radicals
Citation
Alva Sathyavathi, Paramesha S, Kumari N Suchetha, Gowda K M Damodara, Mahesh. Antioxidant status and serum total protein levels in elderly women. International Journal of Applied Biology and Pharmaceutical Technology. 2011 Jul-Sept; 2(3): 521-524.