Seroprevalence of Malaria and Hepatitis B (HBsAg) with Associated Risk Factors among Pregnant Women Attending Antenatal Clinic in General Hospital Minna, North-Central Nigeria.
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Date
2012-10
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Abstract
Aims: This study determines the antibody levels of Malaria and Hepatitis B and associated
risk factors among pregnant women attending anti-natal Clinic at General Hospital Minna.
Study Design: The subjects were pregnant women who attended ante-natal clinic. Sample
sizes were determined from the number of pregnant women that attended antenatal Clinic.
Place and Duration of Study: Samples were collected from the ante-natal Clinic of
General Hospital Minna between July to November 2011.
Methodology: Samples were assayed for malaria and hepatitis B (HBsAg) by commercial
enzyme-linked immunosorbent assay kits. Time and age of pregnancy were noted.
Results: Out of the 269 pregnant women screened 216(80.30%) were positive for malaria,
22(8.18%) for hepatitis B and 21(7.81%) were co-infection of malaria and hepatitis B and
10 were negative, while non-pregnant women had 51(51.00%), 8(8.00%) and 6(6.00%) for malaria, hepatitis B and co-infection of both out of 100 screened. There was a significant
difference between pregnant and non-pregnant women both in malaria and hepatitis B at
p<0.05. History of blood transfusion, Alcohol consumption and Use of contraceptives were
significantly associated with hepatitis B and co-infection of both hepatitis B and malaria at
p<0.05. Only history of blood transfusion was associated with malaria infection though not
significant.
Conclusion: High prevalence of antibodies to malaria and hepatitis B is a matter of great
concern considering the effect of these diseases on the foetus. Adequate measures need
to be taken to treat and provide prophylactic measures.
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Keywords
Hepatitis, malaria, antigen, alcohol
Citation
Omalu I C J, Jibrin A, Olayemi I K, Hassan S C, Mgbemena C, Mgbemena A, Adeniran L A. Seroprevalence of Malaria and Hepatitis B (HBsAg) with Associated Risk Factors among Pregnant Women Attending Antenatal Clinic in General Hospital Minna, North-Central Nigeria. Annual Review & Research in Biology. 2012 Oct-Dec; 2(4): 83-88.