Correlation analysis of frequency distributions of residues in proteins.
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Date
1995-01
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Abstract
Autocorrelation and spectrum analyses of amino acid residues along protein
chains in a large data base has been performed. Results reveal the presence of general
long range correlations. Similar analyses of simulated (random) peptides do not exhibit any
such long range correlations. Based on the results of nur analysis, an attempt has been
made to model the distribution of residues in protein sequences on a fractional Brownian
motion and individual sequences as multi-fractals. For this purpose, the characteristics of
an fractional Brownian motion namely, the scaling parameter H. the spectral exponent β
and the fractal dimension D, have been described.
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Keywords
Protein sequences, long range correlations, fractals, fractional Brownian motions
Citation
Rani Meeta, Mitra Chanchal K. Correlation analysis of frequency distributions of residues in proteins. Journal of Biosciences. 1995 Jan; 20(1): 7-16.