Control of transcription initiation.
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Date
1993-03
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Abstract
Mechanism of control of transcription initiation have expanded far beyond the
classical operon concept. Control elements are multipartite and well separated from each
other. The trans-factors bound to these sites make contacts with RNA polymerase: promoter
complexes by DNA bending or looping to influence the initiation event. Activators and
repressors are like two faces of the same coin and their function depends on the site of
action, mode of interaction with DNA and also the nutritional status of the cell.
Description
Keywords
RNA polymerase, promoter, activator, repressor, transcription
Citation
Nagaraja V. Control of transcription initiation. Journal of Biosciences. 1993 Mar; 18(1): 13-25.