Role of nicotinic acid as modulator of liposomal microviscosity.
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Date
1990-09
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Abstract
Using the fluorescent probe 1,6-diphenyl-1,3,5 hexatriene, we have investigated
the effect of nicotinic acid, a derivative of the toxic alkaloid nicotine, on the fluidity profile
and activation energy of diffusion in the liposomal system of several lipids. We have also
studied how the fluidizing property of nicotinic acid affects the intermediate fluid condition
induced by cholesterol in these liposomal systems.
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Keywords
Nicotinic acid, phospholipid, fluidity, phase transition
Citation
Chatterjee M, Basu R, Nandy P. Role of nicotinic acid as modulator of liposomal microviscosity. Journal of Biosciences. 1990 Sep; 15(3): 145-148.