Adrenocorticotrophin secreting cells in the hypophysis of the brown spiny mouse Mus platythrix (Bennett).
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Date
1984-06
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Abstract
Adrenocorticotrophin secreting cells are identified in the hypophysis of the brown
spiny mouse Mus platythrix by conventional methods of light microscopy. Quantitative data
showed that certain smaller acidophilic cells in the pars distalis, under conditions provoking
their hypersecretion such as unilateral adrenalectomy and metopirone treatment, increase in
number and size from the pre-existing corticotrophs. There is no evidence for the
transmigration of these cells from the chromophobes, basophils or any other cell type. The pars
intermedia revealed two types of cells of which the type II cells are histochemically identical to
adrenocorticotrophin secreting cells of the pars distalis.
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Keywords
mouse, adrenocorticotropic secreting cells, metopirone, unilateral adrenalectomy, cold stress, histochemistry
Citation
Dutt N H Gopal, Madhyastha N A. Adrenocorticotrophin secreting cells in the hypophysis of the brown spiny mouse Mus platythrix (Bennett). Journal of Biosciences. 1984 June; 6(2): 193-202.