Molecular Analysis Of The Additional X-Chromosome In Klinefelter's Syndrome Patients.
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Date
1995-01
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Abstract
The parental origin of the extra X chromosome in five families with Klinefelter's syndrome (47,XXY) was studied DNA restriction fragment length polymorphisms (RFLPs). In four, the extra X chromosome was maternal in origin and one it was paternal. Four X-linked marker loci were used and we were able to specify the origin of the extra X chromosome in all cases.
The parental origin of the extra X chromosome in five families with Klinefelter's syndrome (47,XXY) was studied DNA restriction fragment length polymorphisms (RFLPs). In four, the extra X chromosome was maternal in origin and one it was paternal. Four X-linked marker loci were used and we were able to specify the origin of the extra X chromosome in all cases.
The parental origin of the extra X chromosome in five families with Klinefelter's syndrome (47,XXY) was studied DNA restriction fragment length polymorphisms (RFLPs). In four, the extra X chromosome was maternal in origin and one it was paternal. Four X-linked marker loci were used and we were able to specify the origin of the extra X chromosome in all cases.
The parental origin of the extra X chromosome in five families with Klinefelter's syndrome (47,XXY) was studied DNA restriction fragment length polymorphisms (RFLPs). In four, the extra X chromosome was maternal in origin and one it was paternal. Four X-linked marker loci were used and we were able to specify the origin of the extra X chromosome in all cases.
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Keywords
Klinefelter"s Syndrome, Extra X, RELP study
Citation
Mohapatra I, Kucheria K, Ammini A C. Molecular Analysis Of The Additional X-Chromosome In Klinefelter's Syndrome Patients. Indian Journal of Human Genetics. 1995 Jan; 1(1): 20-26.