Superbugs causing ventilator associated pneumonia in a tertiary care hospital and the return of pre‑antibiotic era.
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Date
2015-04
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Abstract
The rise in super bugs causing Ventilator‑Associated Pneumonia (VAP) is a major cause of mortality and morbidity
despite recent advances in management owing to the looming ‘antibiotic apocalypse’. The aetiology and susceptibility
pattern of the VAP isolates varies with patient population, type of intensive care unit (ICU) and is an urgent diagnostic
challenge. The present study carried out for a period of one year in a tertiary care hospital, enrolled patients on
mechanical ventilation (MV) for ≥48 hrs. Endotracheal aspirates (ETA) from suspected VAP patients were processed
by semi quantitative method. Staphylococus aureus, members of Enterobacteriaceae were more common in early onset
VAP (EOVAP), while Nonfermenting Gram negative bacilli (NFGNB) were significantly associated with late onset
VAP (LOVAP). Most of the isolates were multi drug resistant (MDR) super bugs. With limited treatment options left for
this crisis situation like the pre‑antibiotic era; it is an alarm for rational antibiotic therapy usage and intensive education
programs.
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Keywords
Endotracheal aspirate, non fermenting gram negative bacilli, superbugs, ventilator associated pneumonia
Citation
Qureshi S, Agrawal C, Madan M, Pandey A, Chauhan H. Superbugs causing ventilator associated pneumonia in a tertiary care hospital and the return of pre‑antibiotic era. Indian Journal of Medical Microbiology. 2015 Apr; 33(2): 286-289.