Phytochemical screening and evaluation of analgesic and antiinflammatory activities of Phaseolus vulgaris linn., seeds in rodents.
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Date
2015-06
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Abstract
With an objective of developing some novel analgesic and antiinflammatory natural agents with fast acting and
low toxicity profile here in, the different extracts of Phaseolus vulgaris (Linn) seeds were evaluated for analgesic
and antiinflammatory activities using glacial acetic acid induced writhing and carrageenan induced rat paw
oedema method respectively. For screening of the extracts for analgesic and antiinflammatory activities aspirin
and diclofenac were used as standard drugs respectively. Petroleum ether extract exhibited significant analgesic
and antiinflammatory activities. The petroleum ether extract can be considered as a potential candidate for
analgesic and antiinflammatory activities. The presence of steroids and flavonoids in petroleum ether extract of
Phaseolus vulgaris Linn., seeds could be attributed for the analgesic and antiinflammatory activities.
Description
Keywords
Analgesic, Antiinflammatory, Phaseolus, vulgaris Linn, seeds, carrageenan, glacial acetic acid
Citation
Pradeepkumar M R, Joshi Shrinivas D, Kulkarni V H, Savant Chetan. Phytochemical screening and evaluation of analgesic and antiinflammatory activities of Phaseolus vulgaris linn., seeds in rodents. Journal of Applied Pharmaceutical Science. 2015 June; 5(6): 66-69.