Phytochemical screening and evaluation of analgesic, anti-antiinflammatory activities of Peganum harmala Linn., seeds in rodents.
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Date
2015-05
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Abstract
The objective of this research work is to carryout the phytochemical screening and evaluate the analgesic, antiinflammatory
activities of Peganum harmala Linn., seeds. In this study different extracts of Peganum harmala
(Linn) seeds were evaluated for analgesic and anti-inflammatory activities using glacial acetic acid induced
writhing and carrageenan induced rat paw edema models respectively. For analgesic and anti-inflammatory
activities aspirin and diclofenac were used as standard drugs respectively. The ethyl acetate extract showed
significant analgesic and anti-inflammatory activities, thus it can be considered as a potential candidate for
analgesic and antiinflammatory activities. The presence of alkaloids, steroids, flavonoids in ethyl acetate extract
of Peganum harmala (Linn) seeds could be attributed for the claimed analgesic and anti-inflammatory activities.
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Keywords
Peganum harmala, Zygophyllaceae, analgesic, anti-inflammatory, carrageenan
Citation
Kumar M R Pradeep, Joshi Shrinivas D, Kulkarni V H, Savant Chetan. Phytochemical screening and evaluation of analgesic, anti-antiinflammatory activities of Peganum harmala Linn., seeds in rodents. Journal of Applied Pharmaceutical Science. 2015 May; 5(5): 52-55.