Epidemiological study of active Hepatitis B and C viruses’ infection among patients attended in tertiary care hospital in Dhaka City, Bangladesh.
Loading...
Date
2014-09
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Viral hepatitis is a major global public health problem and both hepatitis B virus (HBV) and hepatitis C virus
(HCV) infections are rapidly spreading in the developing countries including Bangladesh. A molecular
characteristic-based epidemiological study was conducted to identify the Molecular Characterization of Hepatitis
B and C Viruses in Dhaka City, Bangladesh among all age groups, gender and marital status and to identify the
possible risk factors for acquiring the infections. Informed consent was taken from every individual being tested
and approval was obtained from institutional ethical review committee. Using the Enzyme-Linked
Immunosorbent Assay for 1855 blood samples, our study clearly indicated a high prevalence of active HBV and
HCV as 8.0% and 3.0% respectively in general public of Savar, Dhaka. Both HBV and HCV prevalence varied
significantly in different age groups with respect to gender and marital status. In case of HBV, it was least
prevalent for individuals whose age was above 60 years. Contrary in case of HCV, it was least prevalent for
individuals whose age was below 11 years and above 60 years. However, middle aged populations, especially
31–40 and 21–30 year individuals were observed at higher risk of hepatitis B and C ailments with 11.28% active
HBV prevalence and 5.77% active HCV prevalence with respect to gender, respectively. The findings and further
studies of genotype distribution might guide eventually the development, adaptation and evaluation of prevention
strategies.
Description
Keywords
Hepatitis B and C viruses, infection, Epidemiology, Prevention strategies, Enzyme-Linked, Immunosorbent Assay (ELISA)
Citation
Uddin Kazi Rasel, Aktet Salina, Jinnah Chaklader Md Kamal, Talukder Ali Azam. Epidemiological study of active Hepatitis B and C viruses’ infection among patients attended in tertiary care hospital in Dhaka City, Bangladesh. Journal of Applied Pharmaceutical Science. 2014 Sept; 4(9): 102-109.