Intraosseous primary malignant peripheral nerve sheath tumor of the calcaneus: An unusual case and review of literature.
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Date
2015-04
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Abstract
Malignant peripheral nerve sheath tumors (MPNSTs) are uncommon sarcomas
that originate from a peripheral nerve or neurofi broma either spontaneously or in
association with neurofi bromatosis type 1. MPNSTs account for approximately
5% of all soft tissue malignancies. The tumor is commonly seen in the extremities
and trunk. Most of these tumors are high-grade with the potential to recur and
metastasize. Common metastatic sites include the lungs, bone, and pleura.
Primary intraosseous MPNST is rare, and the diagnosis of intraosseous
MPNST, especially in an unusual location is diffi cult because of its cellular
origin, histomorphological similarities with other sarcomas, and bone is the
most common site for metastasis. We report an unusual case of MPNST of the
calcaneus in a young male.
Description
Keywords
Bone, calcaneus, malignant peripheral nerve sheath tumors, S-100
Citation
Gahlot Gaurav Pratap Singh, Mridha Asit Ranjan, Nath Devajit, Khan Shah Alam, Gamanagatti Shivanand. Intraosseous primary malignant peripheral nerve sheath tumor of the calcaneus: An unusual case and review of literature. Indian Journal of Pathology & Microbiology. 2015 Apr-Jun 58(2): 220-222.