Anticoagulation dilemma in a high‑risk patient with On‑X valves.
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Date
2015-04
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Abstract
Thromboembolism continues to be a major concern in patients with mechanical heart valves, especially in
those with unsatisfactory anticoagulation levels. The new On‑X valve (On‑X Life Technologies, Austin, TX,
USA) has been reported as having unique structural characteristics that offer lower thrombogenicity to the
valve. We report a case where the patient received no or minimal systemic anticoagulation after placement
of On‑X mitral and aortic valves due to development of severe mucosal arterio‑venous malformations yet
did not show any evidence of thromboembolism. This case report reinforces the findings of recent studies
that lower anticoagulation levels may be acceptable in patients with On‑X valves and suggests this valve
may be particularly useful in those in whom therapeutic levels of anticoagulation cannot be achieved due
to increased risk of bleeding.
Description
Keywords
Anticoagulation, On‑X valve, Thromboembolism
Citation
Karkar Ami M, Castresana Manuel R, Odo Nadine, Agarwal Shvetank. Anticoagulation dilemma in a high‑risk patient with On‑X valves. Annals of Cardiac Anaesthesia. 2015 Apr; 18(2): 257-260.