Novel approach in formulation and evaluation of mouth dissolving tablets of ondansetron hydrochloride.
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Date
2010-08
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Abstract
Mouth dissolving drug delivery systems has number of advantage viz., faster onset of action,
elegance, ease of administration, ease of manufacturing, ease of storage and transport. A novel attempt has been
made to develop mouth dissolving tablets of Ondansetron hydrochloride by including clove oil as flavor and
local anesthetic on taste buds. The tablets were prepared by direct compression technique. The formulated
tablets were evaluated for Pre formulation and post formulation parameters and they were found to be
saatisfactory. Direct compression method was employed for making mouth dissolving tablets. The formulated
mouth dissolving tablets possessed good drug releasing property, good mouth feel and improved drug
availability with better patient compliance.
Description
Keywords
Mouth dissolving tablet, Ondansetron hydrochloride, direct compression method, superdisintegrants
Citation
Ahad Hindustan Abdul, Anuradha C M, Kumar Chitta Suresh, Reddy B Kishore Kumar, Kumar D Jagadeesh. Novel approach in formulation and evaluation of mouth dissolving tablets of ondansetron hydrochloride. International Journal of Applied Biology and Pharmaceutical Technology. 2010 Aug-Oct; 1(2): 582-588.