Management Practices in Hypertension : Results of WIN-OVER — A Pan India Registry.
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Date
2015-02
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Abstract
Hypertension is a common disease seen in
clinical practice and is associated with high morbidity and
mortality. Many patients require combination therapy for
the management of hypertension. Objective: To evaluate
co-morbidities, risk factors and management practices of
hypertension in Indian population. Material and methods:
A total of 1596 hypertensive adult patients received antihypertensive
medications were studied in a cross-sectional,
multi-centric, non-interventional, observational registry.
Statistical analysis: Categories or nominal data was
expressed as numbers with percentages. Continuous
variables were analyzed by descriptive statistics using mean,
SD, and range Chi square test was used for in between
group comparison. Results: The study included 73.50%
males and 26.50% females. Overweight (50.50%) and
obesity (30.01%) was common in the hypertensive patients
(n=903). A total of 54.76% patients had history of smoking.
Alcohol use (33.08%), sedentary life style (32.96%) and
history of tobacco chewing (17.92%) were the other
lifestyle habits of hypertensive patients. Diabetes (36.03%)
and dyslipidemia (39.79%) history was common in these
patients. Family history of hypertension and diabetes was
seen in 82.21% and 45.99% patients respectively. Most
(89.16%) patients were treated with combination of
antihypertensive agents. ARBs were the by far most
commonly used agents (91.98%) followed by calcium
channel blockers (68.23%) and diuretics (60.21%). ARB
was the most (80.35%) preferred agent as monotherapy.
ARB was also the most common agent as a component of
dual therapy, four drug and five drug combinations.
Conclusion: Most of the hypertensive patients need
combination treatment with antihypertensive agents. ARBs
are the most preferred agents as monotherapy for the
management of hypertension. ARBs are also very commonly
used as a component of combination therapy during
hypertension management.
Description
Keywords
antihypertensive, hypertension, management
Citation
Trailokya Abhijit, Patel Kamlesh, Dalvi Kalpesh. Management Practices in Hypertension : Results of WIN-OVER — A Pan India Registry. Indian Medical Gazette. 2015 Feb ; 149 (2): 62-67.