Prevalence of Left Ventricular Diastolic Dysfunction in Patients with Normal Systolic Function and its Relation with Other Risk Factors from Eastern India.
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Date
2015-02
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Abstract
Impaired diastolic filling
of left ventricle may be the important cause of symptoms
ranging from mild to severe form of dyspnea with overt
features of pulmonary edema which may be wrongly
imparted to systolic failure. To study prevalence and severity
of diastolic dysfunction and its relation with various risk
factors. Methods: Patients from in and out patients
department were subjected to detail history, estimation of
BMI, blood sugar levels, BP measurement,
echocardiographic assessment of cardiac function. Patients
of isolated diastolic dysfunction were identified and the
degree of diastolic dysfunction was correlated with
functional class (NYHA grade) of the patients as well as
various risk factors. Results: Out of 400 patients 16 (12.5%)
asymptomatic patients had diastolic dysfunction (DD).
Severity of diastolic dysfunction increased as the presenting
NYHA grade was higher. In NYHA grades III and IV, 59%
and 57% of the patients respectively had diastolic
dysfunction .DD was significantly associated with diabetes
(p<.0001), BMI (p =0.0002), dyslipidemia (p =0.0491),
hypertension (p=0.0489). Conclusion: DD is a significant
cardiac morbidity. Hypertension, diabetes, dyslipidemia and
obesity have significant association with diastolic
dysfunction. There is no randomized control trials for
treatment for DD. Whether asymptomatic DD needs
treatment is not known.
Description
Keywords
diastolic dysfunction, metabolic syndrome, dyspnea, NYHA grading
Citation
Paul Rudrajit, Maiti Animesh, Sinha Pradip Kr, Mukherjee Soura, Mookherjee Sekhar, Kumar Dey Sujit, Raychaudhuri Pradip. Prevalence of Left Ventricular Diastolic Dysfunction in Patients with Normal Systolic Function and its Relation with Other Risk Factors from Eastern India. Indian Medical Gazette. 2015 Feb ; 149 (2): 54-61.