Skin Tumours – Histopathological Review of 125 Cases.
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Date
2014-11
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Abstract
The skin is the largest organ in the body. A wide variety
of hyperplastic growths and tumours, both benign and
malignant are encountered in the clinical practice. Any
lesion, for which the diagnosis is uncertain, based on the
history and clinical examination should be biopsied for
histopathological examination to rule out malignancy.
Objective: To analyze retrospectively tumours of skin with
respect to age, sex, clinical features and histopathological
features in a tertiary referral centre in Maharashtra, India.
Material & Methods: The present study consisted of
analysis of tumours of skin received in the histopathology
section of department of pathology over a period of 5 years
that is from August 2005 to July 2010. The material
comprised of biopsies and excision specimens. The clinical
and histopathological details were noted. The findings were
compared with those reported by other authors. Results:
One twenty five (125) tumours of skin were observed.
The benign tumours were slightly more common (51.2%)
than malignant tumours (48.8%). The maximum number
of tumours was found in 7th decade (25.6%). Maximum
number of tumours were found in third decade in benign
tumours (20.3%) and seventh decade in malignant tumours
(37.7%). Both benign and malignant tumours of skin were
common in males than females. The equal numbers of skin
tumours were seen in both the head and neck region
(44.8%) and the extremities (44.8%). Face was the
commonest site for skin tumours (35.2%). The keratinocytic
tumours, both benign and malignant were common tumours
of skin (62.4%) while neural tumours were rarely observed
(1.6%). The Squamous Cell Carcinoma (SCC) was the
commonest malignant tumour (45.9%) followed by Basal
Cell Carcinoma (BCC) (34.4%). Verrucas (32.8%) were
the commonest benign tumours followed by pyogenic
granuloma (21.9%). Conclusion: SCC is the most common
malignant skin tumour in India, unlike the Western countries.
Histopathological study is a very important step in the
diagnosis of skin tumours.
Description
Keywords
skin, tumours, histopathology
Citation
Bari Vaibhav, Gosavi Alka, Murarkar Prashant, Sulhyan Kalpana. Skin Tumours – Histopathological Review of 125 Cases. Indian Medical Gazette. 2014 Nov ; 148 (11): 418-427.