Significance of Coagulase Negative Staphylococci with Special Reference to Species Differentiation and Antibiogram.
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Date
2014-07
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Abstract
Coagulase negative staphylococci
(CoNS)are part of normal human flora increasingly
recognized as significant nosocomial pathogens, infection
often associated with implanted devices, joint prosthesis
and different indwelling devices, especially in very young,
old immunocompromised patients. Aims: To identify CoNS
species, their distribution and antibiotic susceptibility pattern
from different clinical samples. Method: A total 185 CoNS
isolates were collected from various clinical samples followed
for species identification by a practical scheme adapted
using simple ,useful test selected from various references.
Antibiotic susceptibility done by Kirby Bauer disc diffusion
method. Results: The study yield that 185 CoNS,strains
were isolated out of 1514 positive cultures from various
clinical specimens. Among species ; S. epidermidis was
the most commonly isolated species (68.65%), followed
by S. heamolyticus (16.75%),followed by S.
saprophyticus(9.8%)and few other species also identified.
The antibiotic susceptibility pattern against commonly used
antibiotic showed multidrug resistance with more than 90%
resistance to penicillin and no strains was resistance to
vancomycin. The methicillin resistance was 63% among
all isolates of CoNS. Conclusions: Study suggest increasing
pathogenic potential of CoNS as well as emerging of drug
resistance amongst them, that necessitates the need to adopt
simple laboratory procedure to identify CoNS species and
understand definitive therapy for CoNS isolates from various
clinical samples. This scheme was able to identified 98.9%
isolates up to species level.
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Keywords
Coagulase negative Staphylococci (CoNS) species, identification, antibiotic susceptibility pattern
Citation
Parashar Sadhvi. Significance of Coagulase Negative Staphylococci with Special Reference to Species Differentiation and Antibiogram. Indian Medical Gazette. 2014 Jul ; 148 (7): 255-258.