Clinical Profile of the H1N1 Influenza.
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Date
2014-07
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Abstract
The H1N1 influenza A infection initially
pandemic started in Mexico in March 2009 and spread as
per WHO phases of pandemic alert all over the world. It
was in late march 2009 an outbreak of a respiratory illness
and later to proved to be caused by novel swine
origin influenza A (S-OIV) identified in Mexico. Aims &
Objectives : The aim of the present study was to describe
first clinical presentation, various organ damage, treatment
outcome duration of hospital stay and mortality and impact
on high risk group patients. This is retrospective study
hospital based Bharati Vidyapeeth Deemed University
Medical College and Hospital, Sangli. Material and
Methods: During post-pandemic period in 2010 the patients
were admitted in hospitals which were suspected cases of
H1N1 influenza “A” infection. 118 cases were studied
August 2010 to 31st January 2011. Results : One hundred
eighteen (118) patients were admitted in hospital. Of the
118 patients 32 patients were H1N1 positive and 86 patients
H1N1 negative. RT- PCR test was done for confirmation
of infection. X- Ray chest in positive cases of H1N1
influenza “A” infection bilateral extensive Pneumonititis other
organ damage suggestive ECG, STT were changes renal
failure common symptoms cough, fever, breathlessness in
28 cases sex-wise and age-wise distribution is not
significant. Hospital stay all admitted patients and hospital
stay in expired patients p value < 0.00 and < 0.005 highly
significant. Statistics – percentage, ratio Chi- square tests
used. Conclusion : Mortality in risk (Comorbid condition)
with and without risk (ventilator required) The Mortality
was 18.50 % more during the winter season (Chilly and
cold atmosphere August to October during this season
feverable for viability of the virus) significantly mortality is
seen in young age group. This infection can be prevented
by vaccination. The tablet tamiflu 75 mg 1 BD for 10 days
no other adverse effects observed in our study the drug is
safe and no resistance was observed.
Description
Keywords
clinical profile H1N1 influenza “A” infection, ARDS/ pneumonititis
Citation
Jadhav V B, Shravasti R K, Borade V B, Palange P B, Kulkarni R B. Clinical Profile of the H1N1 Influenza. Indian Medical Gazette. 2014 Jul ; 148 (7): 237-244.