Review of Mesna (Mistabron) as a Mucolytic for Preventing Plumonary complications in Intensive Care Setting.

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2014-06
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Abstract
Impaired mucus clearance or mucus hypersecretion are important feature of many pathological respiratory conditions and in ICU patients. Mesna is a potent mucolytic available as 200 mg/ml solution for neublization and endotracheopulmonary instillation. As effective “mucus clearance” is critical in managing post-operative and other ICU conditions to prevent complications like atelectasis and hypoxia, there is a need to review the clinical results of mucolytic agent Mesna, and its role in mucociliary clearance in critical care patients and in other respiratory conditions.
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Waghray Pradyut, Dongre Prashant. Review of Mesna (Mistabron) as a Mucolytic for Preventing Plumonary complications in Intensive Care Setting. Indian Medical Gazette. 2014 Jun ; 148 (6): 218-225.