Spectrum of Histopathological Findings in Liver Biopsy.
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Date
2013-10
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Abstract
The significance of abnormal liver function tests in the
absence of diagnostic serology is unclear. The aim of this
prospective study is to report liver biopsy findings in a
large group of patients with unexplained abnormal liver
biochemistry and correlate them with the clinical features
to assess the severity of these diseases. Percutaneous liver
biopsy is a relatively safe and accurate method of diagnosing
liver disease and should be considered in such cases. A
total of 65 liver biopsies were studied, of which, 26.15%
(n=17) hepatic tumors, 23.08% (n=15) cirrhosis, 20.00%
(n=13) fatty liver and 06.15% (n=4) viral hepatitis were
seen. Further, 01.54% case (n=1) each of alcoholic
hepatitis, benign recurrent intrahepatic cholestasis,
extrahepatic biliary atresia, granulomatous hepatitis, neonatal
hepatitis, Niemann-Pick disease and secondary biliary
cirrhosis were also observed. Liver biopsy was non specific
in 9.23% (n=6) and inadequate in 4.62% (n=3) cases .The
role of histopathological examination of liver biopsy is
highlighted in this paper.
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Keywords
liver biopsy, histopathological examination
Citation
Chawla Nitin, Sunila S. Spectrum of Histopathological Findings in Liver Biopsy. Indian Medical Gazette. 2013 Oct ; 147 (10): 363-367.