Lipoprotein(a) in Essential Hypertension Patients.
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Date
2013-08
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Abstract
Background: Lipoprotein(a) [Lp(a)] is an important and
independent cardiovascular risk factor, but its role in the
development of coronary vascular disease in hypertensives
have conflicting results. Adequate studies have not been
conducted on the Lp(a) in essential hypertensive patients.
Aims and Objectives: In the present study, we aimed to
investigate the possible relationship between plasma Lp (a)
and lipid levels in essential hypertensive patients. Materials
and Methods: A total of 30 essential arterial hypertensive
patients were studied and compared with 30 controls
matched in terms of age, sex and body mass index. Results:
It was seen that mean level of Total Cholesterol,
Triglyceride, Very Low Density Lipoprotein-Cholesterol and
Low Density Lipoprotein-Cholesterol were elevated in
hypertensive patients as compared to controls, but the levels
were not statistically significant. Taking 30 mg/dl as the
cut off value of Lp(a), majority of the patients had levels
more than 30 mg/dl (P<0.001) when compared to controls.
Conclusion: This study indicates that significantly elevated
serum Lp(a) level can be a independent risk factor for
coronary vascular diseases in essential hypertensive
patients.
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Keywords
lipoprotein (a), essential hypertension, lipids, coronary vascular disease
Citation
Singh Solanki Ummed, Kumar Anil. Lipoprotein(a) in Essential Hypertension Patients. Indian Medical Gazette. 2013 Aug ; 147 (8): 292-296.