Patterns of Glomerulonephritis in Uttarakhand State 13 Years Single Centre Experience at Teaching Institute.
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Date
2013-06
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Abstract
Aims : Glomerular disease is considered to be a common
cause of chronic kidney disease and its prevalence and
histological pattern differ according to geographical area,
race, age in different regions of the world. The present
study was therefore conducted to study the pattern of
different histological types of glomerulonephritis in this area
of Uttarakhand region of India over an extended period of
13 years. Material and Methods : Retrospective study was
conducted in the tertiary care centre of Uttarakhand state
which included cases of different types of
glomerulonephritis diagnosed on histopathology over a period
of 13 years. Age, sex, clinical presentation, relevant
investigations and the histopathological type of
glomerulonephritis were noted for every case. Results :
Histopathological examination due to various non-neoplastic
renal diseases was done in total 218 cases and out of these
glomerular diseases was diagnosed in 178 cases. Proteinurea
and edema was the most common presentation. Primary
glomerulonephritis was observed in 88.5% cases and
secondary in 9.9%. Mesangioprolifrative glomerulonephritis
was the most common primary glomerulonephritis and
nephropathy due to amyloidosis was the most common
type of secondary glomerulonephritis. Conclusion : The
study concludes that primary glomerulonephritis is the most
common renal disease with mesangioproliferative
glomerulonephritis as the most common primary
glomerulonephritis and amyloidosis nephropathy as the
most common secondary glomerulonephritis which differs
from other regions of world. The study may be useful to
pathologists, nephrologists and health care providers to
formulate a basic platform for effective diagnostic,
therapeutic and research base for glomerular diseases so
as to prevent its complications.
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Keywords
glomerulonephritis, mesangioproliferative glomerulonephritis, secondary glomerulonephritis
Citation
Chandra Harish, Chandra Smita. Patterns of Glomerulonephritis in Uttarakhand State 13 Years Single Centre Experience at Teaching Institute. Indian Medical Gazette. 2013 Jul ; 147 (6): 220-223.