Effect of Risperidone on Lipid Profile and Related Risk for Coronary Heart Disease.
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Date
2012-07
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Abstract
Present study was carried out in a view to studing the
effect of Risperidone used for treatment of Schizophrenia
on Lipid Profile and, its related risk for coronary heart
disease, in 30 patients on Risperidone and compared with
30 age and sex matched healthy controls. We found that
this drug significantly does not increase the risk for coronary
heart disease in patients with respect to lipid profile and
other parameters as described by Framingham study group
by estimating Framingham Point Scores. Nor it has much
effect on lipid profile, except that triglyceride shows
significantly higher levels (187.1 ± 24.73) as compared to
controls (135.9 ± 25.05) with p value <0.001. Altogether,
this drug is safe for these patients, but long-term
implications of these findings need to be studied, as
prevalence of CHD is increasing day-by-day due to the
globalization.
Description
Keywords
risperidone, schizophrenia, lipid profile, coronary heart disease
Citation
Paunipagar P V, Sharma Rahul, Gumaste Anil. Effect of Risperidone on Lipid Profile and Related Risk for Coronary Heart Disease. Indian Medical Gazette. 2012 Jul ; 145 (7): 266-268.