Study of Lipid Profile and Glycated Hemoglobin in Diabetes Mellitus.
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Date
2012-07
Journal Title
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Abstract
Background: Pattern of dyslipidemia is found to be
different in type-1 & type-2 diabetes mellitus(DM).
Dyslipidemic pattern and its correlation with glycated
hemoglobin in both types of diabetes mellitus has been well
studied and might be informative to the
diagnostic,therapeutic & prognostic aspects of diabetes
mellitus. AIM: To study the lipid profile by using direct
method for High Density Lipoprotein-Cholesterol (HDLC)
& Low Density Lipoprotein-Cholesterol(LDL-C)
estimation, and glycated hemoglobin(GHb) in type-1DM
& type-2 DM. Material and Methods: fifty each already
diagnosed patients of type-1 and type-2 diabetes mellitus
along with fifty control were studied for lipid profile using
direct method for Low Density Lipoprotein-Cholesterol
(LDL-C) & High Density Lipoprotein-Cholesterol (HDLC)
estimation and glycated hemoglobin status. Statistical
Analysis: we used student t-test and Pearson’s correlation
coefficient to find the statistical significance. Result: serum
concentration of glycated hemoglobin and all the parameters
of lipid profile except HDL-C were increased while HDL-C
concentration decreased in both the types of DM as
compared to that of control. Conclusion: dyslipidemia is
more prominent in type-2 DM than that in type-1 DM .
Glycemic control is poorer & its correlation with lipid profile
is stronger in type-2 DM as compared to type-1 DM.
Description
Keywords
diabetes mellitus, lipid profile, glycated hemoglobin, dyslipidemia
Citation
Masram S W, Ghangle Suresh, Bimanpalli M V. Study of Lipid Profile and Glycated Hemoglobin in Diabetes Mellitus. Indian Medical Gazette. 2012 Jul ; 145 (7): 257-265.