Sympathetic Response in Symptom Subgroups of Irritable Bowel Syndrome (IBS).
Loading...
Date
2012-03
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Objective: To evaluate sympathetic adrenergic function
in irritable bowel syndrome (IBS) patients. Methods:
Standard cardiovascular reflex tests were performed on
forty patients with IBS and thirty healthy subjects.
Sympathetic adrenergic function was assessed by
measuring diastolic blood pressure response to hand grip
test (HGT) at 4 min and cold pressor test (CPT) at 1min
and also blood pressure response to head-up-tilt (HUT).
Results: The change in diastolic pressure during (HGT)
and (CPT) of IBS patients were not significantly different
when compared to control. However, tilting resulted in less
marked rise in diastolic pressure (6.14 ± 0.69 vs 12.1 ±
1.24 mmHg; p < 0.05) at 0.5 min and less rise in heart rate
(6.03 ± 1.26 vs 10.35 ± 1.04 per min; p < 0.05) at 1 min in
IBS patients. Conclusion: IBS patients had reduced
sympathetic drive to (HUT) stress; however, subgroups of
IBS had similar autonomic reaction.
Description
Keywords
autonomic function, irritable bowel syndrome
Citation
Punyabati O, Singh M Amuba, Luikham Len Awor. Sympathetic Response in Symptom Subgroups of Irritable Bowel Syndrome (IBS). Indian Medical Gazette. 2012 Mar ; 145 (3): 107-111.