In-vitro antidermatophytic activity of essential oil of Psidium guajava (Linn.).
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Date
2014-04
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Abstract
Dermatophyte with the ability to digest keratine invade and therve on keratinized of human
and animals. In the present study, the activity of essential oil of Psidium guajava (Linn.) was
evaluated against four selected dermatophytes, namely Microsporiumcanis,
Trichophytomruburum, T. verrucossum, T. tonsurans. Dermatophyteswere isolated with the
infected skin, scalp, nail and genital organs of patients from districts hospital, Bareilly.
Griseofulvin was used as a standard antifungal drug against the test dermatophytes. Oil was
extracted through clevenger’s apparatus. Maximum inhibition zone was reported 69 mm
against T. verrucossum followed by 60 mm Trichophytomruburum, 48 mm
Trichophytomruburum and 45mm Microsporiumcanis. All five concentrations of oil showed
excellent inhibitory effect against all test dermatophytes as compared to standard antifungal
used.
Description
Keywords
Antidermatophytic, Essential oil, Psidium guajava, Griseofulvin, Inhibition zone
Citation
Bhushan Gaurav, Kr Sharma Santosh, Kumar Saurabh, Tandon Rajat, Singh A P. In-vitro antidermatophytic activity of essential oil of Psidium guajava (Linn.). Indian Journal of Pharmaceutical & Biological Research. 2014 Apr-Jun ; 2 (2): 57-59.