Bacteriostatic activity of con a lectin from Canavalia ensiformis.
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Date
2013-10
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Abstract
The aim of this work was to explore the therapeutic applications of Con A lectin from
Canavalia ensiformis and to explore its antibacterial activity. Activity of lectin was quantified
by their ability to agglutinate erythrocytes using Hemagglutination assay. Characterization
and purity of Con A lectin was evaluated by using SDS-PAGE analysis. The reversal of
hemagglutination activity of lectin was evaluated by using the sugars namely; mannose,
galactose, lactose, fructose, glucose. The antibacterial activity of lectins was tested against
Streptococcus mutans, Staphylococcus aureus, Bacillus subtilis, Escherichia coli using pour
plate method. Amoxycillin was used as standard. At 250mg/ml concentration Con A lectin
showed good bacteriostatic activity.
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Keywords
Con A, Gel Electrophoresis, Hemagglutination Assay
Citation
Kulkarni S R, Tayade V J. Bacteriostatic activity of con a lectin from Canavalia ensiformis. Indian Journal of Pharmaceutical & Biological Research. 2013 Oct-Dec ; 1 (4): 59-63.