U.V.Spectrophotometric Method development for Capecitabine in Eudragit and chitosan based Mecrospheres and its Validation.
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Date
2013-07
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Abstract
A simple, rapid, accurate, precise, and economic Spectrophotometric method for Capecitabine in bulk and formulated microspheres dosage form has been developed. Capecitabine shows absorbance maximum at different
wavelength in different solvents, so absorbance was measured and the same wavelengths used for the estimation of
Capecitabine in respective solvents. Capecitabine obey the beer lamberts’ law. Method is validated according to ICH
guideline and carried out for analysis of Capecitabine in pure and formulated microsphere dosage form.
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Keywords
Capecitabine, Microspheres dosage form, UV-Spectrophotometer, Validation
Citation
Kumbhar S C, Salunkhe V R, U.V.Spectrophotometric Method development for Capecitabine in Eudragit and chitosan based Mecrospheres and its Validation. Indian Journal of Pharmaceutical & Biological Research. 2013 Jul-Sept; 1 (3): 32-38.