Synthesis and microbial screening of 6-pyridin-4-yl-2, 3-dihydro-1Hpyridazin-pyridazin-4-one derivatves.
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Date
2013-07
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Abstract
6-pyridin-4-yl-2, 3-dihydro-1H-pyridazin-4-one derivatives were synthesized by a simple method. The isonicotinic
acid hydrazide was made to react with acetaldehyde and acetone. This results into the formation of the respective
hydrazones. These hydrazones formed were cyclized to the pyridazine derivatives. All synthesized compounds were
subjected to antimicrobial activity.
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Keywords
6-pyridin-4-yl-2, 3-dihydro-1H-pyridazin-4-one, hydrazones, cyclization
Citation
Athar Javed, Bhatia M S, Shinde Mayuresh, Singh Vinod. Synthesis and microbial screening of 6-pyridin-4-yl-2, 3-dihydro-1Hpyridazin-pyridazin-4-one derivatves. Indian Journal of Pharmaceutical & Biological Research. 2013 Jul-Sept; 1 (3): 1-7.