Outbreak of Pneumocystis jirovecii pneumonia in renal transplant recipients on prophylaxis: Our observation and experience.
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Date
2014-07
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Abstract
Pneumocystis jirovecii is a life‑threatening opportunistic pathogen affecting immunocompromised hosts, especially
renal transplant recipients. This study reports an outbreak of seven such cases, both inpatients and outpatients, occurring
in our hospital over a period of 4 months (January–April 2013). All patients were male with a median age of 38 years
(range, 28–58 years); the median period between transplantation and diagnosis was 39.5 months (range, 11–123 months).
One patient succumbed to the infection. Two were breakthrough cases, developing the infection while on prophylaxis,
highlighting the need to view prophylaxis in light of the immunosuppression and clinical picture of such patients.
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Keywords
Pneumocystis jirovecii, prophylaxis, renal transplant recipients
Citation
Chandola P, Lall M, Sen S, Bharadwaj R. Outbreak of Pneumocystis jirovecii pneumonia in renal transplant recipients on prophylaxis: Our observation and experience. Indian Journal of Medical Microbiology. 2014 Jul-Sept ; 32 (3): 333-335.