Transcatheter arterial embolization of acute gastrointestinal tumor hemorrhage with Onyx.
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Date
2014-02
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Abstract
BACKGROUND: Endovascular embolization has been used to control gastrointestinal tumor bleeding. Lots of embolic agents have been applied
in embolization, but liquid embolic materials such as Onyx have been rarely used because of concerns about severe ischemic complications.
AIM: To evaluate the clinical efficacy and safety of transcatheter arterial embolization (TAE) with Onyx for acute gastrointestinal tumor hemorrhage.
MATERIALS AND METHODS: Between September 2011 and July 2013, nine patients were diagnosed as acute gastrointestinal tumor hemorrhage
by clinical feature and imaging examination. The angiographic findings were extravasation of contrast media in the five patients. The site of
hemorrhage included upper gastrointestinal bleeding in seven cases and lower gastrointestinal bleeding in two cases. TAE was performed using
Onyx in all the patients, and the blood pressure and heart rate were monitored, the angiographic and clinical success rate, recurrent bleeding
rate, procedure related complications and clinical outcomes were evaluated after therapy. The clinical parameters and embolization data were
studied retrospectively. RESULTS: All the patients (100%) who underwent TAE with Onyx achieved complete hemostasis without rebleeding and
the patients were discharged after clinical improvement without a second surgery. No one of the patients expired during the hospital course. All
the patients were discharged after clinical improvement without a second surgery. Postembolization bowel ischemia or necrosis was not observed
in any of the patients who received TAE with Onyx. CONCLUSIONS: TAE with Onyx is a highly effective and safe treatment modality for acute
gastrointestinal tumor hemorrhage, even with pre‑existing coagulopathy.
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Keywords
Acute, arterial embolization, gastrointestinal hemorrhage, Onyx
Citation
Sun CJ, Wang CE, Wang YH, Xie LL, Liu TH, Ren WC. Transcatheter arterial embolization of acute gastrointestinal tumor hemorrhage with Onyx. Indian Journal of Cancer. 2014 Feb; 51(6_Suppl): s56-59.