Rare Haemoglobin Variant Hb J Meerut in 27 Years Old Female - A Case Report.
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Date
2014-09
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Abstract
Hemoglobin has plenty of variants and fast moving hemoglobins (FMH’s) are the rare hemoglobin
variants. They are having tendency to migrate anodally to hemoglobin A on alkaline gel electrophoresis.
Because of the mutation in the globin genes, these hemoglobin variants have the fast moving nature. The basic
pathophysiology behind it is the substitution of a negatively charged amino acid residue in either α, β or γ
globin chains. Hb J Meerut is an infrequently found α-globin variant. It has previously been reported in various
populations around the world. Here, we are reporting a case of Hb J meerut who came to laboratory for
thalassemia screening.
Description
Keywords
Hb J Meerut, Alkaline gel electrophoresis, fast moving hemoglobins, Globin genes
Citation
Rathod Gunvanti, Aggarwal Sachin, Goyal Rahul, Patel Rushabh, Bhimani Rippal Kumar, Kuchhal N K. Rare Haemoglobin Variant Hb J Meerut in 27 Years Old Female - A Case Report. National Journal of Integrated Research in Medicine. 2014 Sept-Oct ; 5 (5): 108-110.