Dress Syndrome: Time to Define Treatment Guidelines.
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Date
2014-09
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Abstract
Background: DRESS (Drug rash with eosinophilia and systemic Symptoms) syndrome is a drug
hypersensitivity syndrome which begins around 2- 6 weeks after exposure to a drug. If treated early, can
recover completely and much of morbidity can be avoided. Case: A patient with history of taking
carbamazepine for epilepsy, presented with typical features of maculopapular erythematous rash, exfoliative
dermatitis and edema over upper and lower extremities, face, and trunk. He had eosinophilia,
lymphadenopathy and elevated liver enzymes. His condition rapidly improved after withdrawing
carbamazepine and starting steroids. Discussion: The rapid recovery with steroids in this case and in a few
cases reported previously also suggests a need of RCT to assess steroids as an established modality for
management of this severe but curable entity.
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Keywords
Dress Syndrome, Recovery, Steroids
Citation
Singh V P, Muley A, Vaghani A, Patel R, Lodhari J. Dress Syndrome: Time to Define Treatment Guidelines. National Journal of Integrated Research in Medicine. 2014 Sept-Oct ; 5 (5): 106-107.