Genes and oral cancer.
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Date
2014-01
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Abstract
Oral cancers have been one of the leading causes of deaths particularly in the developing countries. Prime reason for this high mortality and morbidity is attributed to the delay in diagnosis and prompt treatment. Relentless research in the field of oncology has led to the advent of novel procedures for the early detection of oral cancers. Molecular biology is highly promising in this regard. It is a procedure that detects alterations at a molecular level much before they are seen under a microscope and much before clinical changes occur. Molecular studies serve as the basis by which we will eventually be able not only to augment clinical assessment and classification of oral lesions but also predict malignant potential of oral lesions, thus reducing the incidence and increasing the scope for early diagnosis and treatment of oral cancers. However, making such sophisticated tools available for the common man in developing countries is one of the most important challenges faced today.
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Keywords
Cytogenetics, intracellular messengers, oncogenes, oral cancer, transcriptional factors, tumor suppression gene
Citation
Jurel Sunit Kumar, Gupta Durga Shanker, Singh Raghuwar D, Singh Mrinalini, Srivastava Shilpi. Genes and oral cancer. Indian Journal of Human Genetics. 2014 Jan-Mar ;20 (1): 4-9.