Eosinophilic angiocentric fibrosis of the orbit: A case report and review of literature.

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Date
2015-01
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Abstract
Eosinophilic angiocentric fi brosis is a rare condition presenting with tumefactive lesions of the nasal cavity, paranasal sinuses, upper respiratory tract and rarely the orbit; and has characteristic histopathological features. We report the case of a 38-year-old lady with a mass lesion in right orbit. Histopathological examination of the biopsy specimen revealed extensive areas of perivascular fi brosis showing a characteristic angiocentric whirling with onion skin pattern; along with perivascular exudates of eosinophils accompanied by collection of plasma cells and lymphocytes. Rheumatology review and autoimmune screening was negative. She underwent surgical debulking followed by tapering course of oral steroids and was completely free of orbital disease at her last follow-up visit.
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Keywords
Angiocentric fi brosis, eosinophilic, orbit, perivascular fi brosis
Citation
Radhakrishnan Santhi, Adulkar Namrata G, Rangarajan Viji. Eosinophilic angiocentric fibrosis of the orbit: A case report and review of literature. Indian journal of pathology& Microbiology 2015 Jan-Mar 58: (1) 77-79.