Evaluation of antifungal susceptibility testing in Candida isolates by Candifast and disk-diffusion method.
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Date
2014-10
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Abstract
With the increase in invasive fungal infections due to Candida species and
resistance to antifungal therapy, in vitro antifungal susceptibility testing is
becoming an important part of clinical microbiology laboratories. Along with
broth microdilution and disk diffusion method, various commercial methods are
being increasingly used for antifungal susceptibility testing, especially in the
developed world. In our study, we compared the antifungal susceptibility patterns
of 39 isolates of Candida to three antifungal drugs (fl uconazole, amphotericin B,
ketoconazole) by Candifast and disk diffusion method. The following resistance
pattern was found by Candifast: Fluconazole (30.8%), ketoconazole (12.8%),
amphotericin B (0%). The results obtained by disk diffusion method were in
complete agreement with Candifast results.
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Keywords
Antifungal, Candida, Candifast, disk diffusion
Citation
Giri Sidhartha, Kindo Anupma Jyoti. Evaluation of antifungal susceptibility testing in Candida isolates by Candifast and disk-diffusion method. Indian Journal of Pathology & Microbiology. 2014 Oct-Dec 57 (4): 595-597.