Diagnostic dilemma in myoepithelial carcinoma of cheek.
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Date
2014-07
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Abstract
Myoepithelial carcinoma (MC) is a rare neoplasm of the salivary gland generally
occurring in the parotid gland and rarely in the minor salivary glands. It poses
a diagnostic challenge on fine-needle aspiration (FNA) cytology because it can
show different cell types and lack clear features of malignancy. This can lead
to a range of differential diagnosis on cytology. The diagnostic difficulty can
be compounded if the lesion is present at an unusual site. A 41-year-old male
presented with a recurrent swelling on the check since 2 years with a prior
history of pleomorphic adenoma (PA) at the same site 8 years back. FNA was
performed and a diagnosis of recurrent PA or myoepithelial cell neoplasm was
given. Final diagnosis was made on histology and immunohistochemistry studies
and reported as MC of minor salivary gland originating within PA. Pathologist
should be aware of the occurrence of MC at the sites of the minor salivary
glands in the oral cavity and its wide morphologic spectrum to make a confident
diagnosis of MC preoperatively.
Description
Keywords
Cheek swelling, fine-needle aspiration, myoepithelial carcinoma, salivary gland neoplasm
Citation
Khatib Yasmeen, Patel Richa D, Kane Shubhada, Khaire Surekha. Diagnostic dilemma in myoepithelial carcinoma of cheek. Indian Journal of Pathology & Microbiology. 2014 Jul-sept 57 (3): 467-469.